Networks are real systems modelled through mathematical objects made up of nodes and links arranged into peculiar and deliberate (or partially deliberate) topologies. Studying these real-world topologies allows for several properties of interest to be revealed. In real networks, nodes are also identified by a certain number of non-structural features or metadata. Given the current possibility of collecting massive quantity of such metadata, it becomes crucial to identify automatically which are the most relevant for the observed structure. We propose a new method that, independently from the network size, is able to not only report the relevance of binary node metadata, but also rank them. Such a method can be applied to networks from any domain, and we apply it in two heterogeneous cases: a temporal network of technology transfer and a protein-protein interaction network. Together with the relevance of node metadata, we investigate the redundancy of these metadata displaying by the results on a Redundancy-Relevance diagram, which is able to highlight the differences among vectors of metadata from both a structural and a non-structural point of view. The obtained results provide insights of a practical nature into the importance of the observed node metadata for the actual network structure.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684645PMC
http://dx.doi.org/10.1038/s41598-019-47717-0DOI Listing

Publication Analysis

Top Keywords

node metadata
16
binary node
8
metadata
8
network structure
8
network
5
evaluating relevance
4
relevance redundancy
4
redundancy quantify
4
quantify binary
4
node
4

Similar Publications

Network analysis is often enriched by including an examination of node metadata. In the context of understanding the mesoscale of networks it is often assumed that node groups based on metadata and node groups based on connectivity patterns are intrinsically linked. This assumption is increasingly being challenged, whereby metadata might be entirely unrelated to structure or, similarly, multiple sets of metadata might be relevant to the structure of a network in different ways.

View Article and Find Full Text PDF

The sample locator: A federated search tool for biosamples and associated data in Europe using HL7 FHIR.

Comput Biol Med

September 2024

German Cancer Consortium (DKTK), DKFZ, Heidelberg, Germany; Federated Information Systems, German Cancer Research Centre (DKFZ), Heidelberg, Germany; Complex Medical Informatics, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Germany; Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Background: This study outlines the development of a highly interoperable federated IT infrastructure for academic biobanks located at the major university hospital sites across Germany. High-quality biosamples linked to clinical data, stored in biobanks are essential for biomedical research. We aimed to facilitate the findability of these biosamples and their associated data.

View Article and Find Full Text PDF

Summary: A problem spanning across many research fields is that processed data and research results are often scattered, which makes data access, analysis, extraction, and team sharing more challenging. We have developed a platform for researchers to easily manage tabular data with features like browsing, bookmarking, and linking to external open knowledge bases. The source code, originally designed for genomics research, is customizable for use by other fields or data, providing a no- to low-cost DIY system for research teams.

View Article and Find Full Text PDF

Background: Instagram (Menlo Park, CA) is a major platform for the dissemination of plastic surgery (PS) information, but the training background of users is difficult to ascertain.

Objectives: We sought to better characterize the source and content of PS-related posts on Instagram.

Methods: Metadata from publicly available Instagram posts containing PS relevant hashtags was collected from December 2018 to August 2020 using Node.

View Article and Find Full Text PDF

The Interactive Tree Of Life (https://itol.embl.de) is an online tool for the management, display, annotation and manipulation of phylogenetic and other trees.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!