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A High-Throughput Method To Measure Relative Quantum Yield of Lanthanide Complexes for Bioimaging. | LitMetric

A High-Throughput Method To Measure Relative Quantum Yield of Lanthanide Complexes for Bioimaging.

Inorg Chem

Department of Chemistry , Stony Brook University, 100 Nicolls Road , Stony Brook , New York 11790 , United States.

Published: August 2019

Luminescent lanthanides provide a promising alternative to organic chromophores for cellular bioimaging and bioassay applications; efficacy is closely governed by their respective quantum yields. Conventionally utilized quantum-yield measurements for lanthanides are laborious and not amenable to rapid relative comparison of compound performance. Here, we introduce a high-throughput optical imaging method to determine and directly compare relative quantum yield using Cherenkov-radiation-mediated excitation of luminescent lanthanide complexes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935265PMC
http://dx.doi.org/10.1021/acs.inorgchem.9b01786DOI Listing

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