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Iodine maps derived from sparse-view kV-switching dual-energy CT equipped with a deep learning reconstruction for diagnosis of hepatocellular carcinoma.
Sci Rep
March 2023
Diagnostic Radiology, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.
Article Synopsis
- Deep learning-based spectral CT imaging (DL-SCTI) enhances image quality by using advanced networks to fill in missing data and improve visual accuracy for dual-energy scans.
- A clinical study involving 52 patients with hypervascular hepatocellular carcinoma (HCC) found that DL-SCTI-generated iodine maps significantly improved the contrast-to-noise ratio (CNR) during the hepatic arterial phase compared to standard 70 keV images.
- While DL-SCTI effectively detects HCCs, it may underestimate iodine concentration in small lesions or lower concentrations, indicating limitations in certain scenarios.
Evaluating image quality and optimal parameters for non-linear blending dual-energy computed tomography images of hepatic portal veins by blending-property-map.
J Xray Sci Technol
August 2022
School of Linguistics, Hebei University of Technology, Tianjin, China.
Background: Blending technology is usually used to improve quality of dual-energy computed (DECT) images.
Objectives: To evaluate the blended DECT image qualities by employing the Blending-Property-Map (BP-Map) and elucidating the optimal parameters with the highest signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR).
Methods: Sixty pairs of 80 kV and 140 kV CT images are blended non-linearly by four methods.
Low kV Computed Tomography of Parenchymal Abdominal Organs-A Systematic Animal Study of Different Contrast Media Injection Protocols.
Tomography
November 2021
Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Rheinische-Friedrich-Wilhelms-Universität Bonn, 53127 Bonn, Germany.
Objectives: To evaluate multiphase low kV computed tomography (CT) imaging of the abdomen with reduced contrast media (CM) dose using different injection protocols.
Methods: Two injection protocols were evaluated for use with low kV (80 kV) multiphase abdominal imaging in comparison to the standard procedure acquired at 120 kV (500 mgI/kg; 5 mL/s). This evaluation was conducted in a highly standardized animal study (5 Goettingen minipigs).
Effect of decreased contrast injection flow rate on aortic enhancement in 80-KV peak CT with contrast dose reduction.
Acta Radiol
January 2023
Department of Radiology, 38146University of Yamanashi, Chuo, Yamanashi, Japan.
Article Synopsis
- The study examines how a decreased injection flow rate of a contrast agent affects aortic enhancement, both through a controlled lab experiment and in a clinical setting.
- In the phantom experiment, a lower flow rate resulted in a slight reduction (6%-9%) in simulated aortic peak enhancement.
- The clinical study found that age was the only significant factor influencing aortic enhancement, while the reduced flow rate didn’t significantly impact aortic enhancement during actual CT scans.
Differences Between CT-Perfusion and Biphasic Contrast-enhanced CT for Detection and Characterization of Hepatocellular Carcinoma: Potential Explanations for Discrepant Cases.
Anticancer Res
March 2021
Department of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.
Aim: To compare the diagnostic value of liver perfusion computed tomography (PCT) and biphasic contrast-enhanced CT (bpCECT) for detection and characterization of hepatocellular carcinoma (HCC), and to identify potential causes for inter-modal discrepancies.
Patients And Methods: In this retrospective study, 162 cases with a total of 325 HCC-typical lesions were evaluated using both PCT and bpCECT (mean time between examinations=15 days, range=0-13 days). HCC diagnosis was performed by multi-modality imaging including lesion growth at follow-up.
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