Evaluation of Bovine-Derived Collagen Membrane in Oral Surgical Mucosal Defects.

Background: The overall purpose of this clinical study is to evaluate the effectiveness of bovine-derived collagen in surgical oral mucosal defects.

Patients And Methods: The study model included thirty-two patients who underwent surgery for benign and malignant lesions of oral cavity in the Indira Gandhi Medical College and Research Institute, Puducherry, India-from 2012 to 2018. The surgical oral mucosal defects had been reconstructed with a commercially available bovine-derived type I collagen [Surgicoll-Mesh, 0.5 mm thick] membrane. The clinical effectiveness of this collagen membrane was evaluated using parameters like haemostasis, pain, epithelialisation, granulation tissue formation and mouth opening as the functional test parameter.

Results: The clinical outcome results documented proved that the bovine-derived collagen membrane showed excellent significant results with respect to haemostasis, pain relief, epithelialisation and granulation tissue formation.