AI Article Synopsis
- A 65-year-old man with advanced pancreatic cancer experienced sudden bilateral blindness and altered sensorium, despite normal eye examinations.
- MRI revealed bilateral parieto-occipital infarcts, indicating that cortical blindness was due to thromboembolism from his cancer.
- As cerebral ischemic events are common at advanced cancer stages and indicate a poor prognosis, anticoagulation therapy, particularly low molecular weight heparin, is recommended to prevent further complications.
Article Abstract
A 65-year-old man, a known case of advanced pancreatic cancer on cisplatin and gemcitabine-based chemotherapy, presented with sudden bilateral painless loss of vision with altered sensorium. Clinical examination showed a normal pupillary light reaction, normal anterior segment and normal fundus. MRI brain showed bilateral parieto-occipital infarct. This report highlights the incidence of cortical blindness due to thromboembolism at the cerebral level in pancreatic cancer. Cerebral ischaemic events occur at an advanced stage of pancreatic cancer already diagnosed at stroke onset and portend a poor prognosis. Anticoagulation therapy, especially low molecular weight heparin, remains the best strategy to prevent recurrences.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677957 | PMC |
| http://dx.doi.org/10.1136/bcr-2017-223843 | DOI Listing |
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