High intensity intermittent training induces anti-inflammatory cytokine responses and improves body composition in overweight adolescent boys.

Horm Mol Biol Clin Investig

University of Mazandaran, Department of Exercise Physiology, Faculty of Sport Sciences, Babolsar, Mazandaran, Iran.

Published: August 2019

Background Anti-inflammatory cytokines, interleukin-4 (IL-4) and interleukin-13 (IL-13) modulate systemic energy metabolism through modifying body composition parameters. Hence, this study aimed at overweight adolescent boys to explore the effect of high intensity intermittent training (HIIT) on these anti-inflammatory cytokines and body composition parameters. Materials and methods Twenty overweight adolescent boys [aged: 18.0 ± 1.5 years, weight: 81.8 ± 4.3 kg, body mass index (BMI): 27.6 ± 0.8 kg/m2] completed this study. The subjects were randomly assigned into two groups of control (CG, n = 10) and training (TG, n = 10). Subjects in the TG performed their training sessions 3 days/week for 6 weeks. The baseline serum values of IL-4 and IL-13 and anthropometric features were measured 1 day before the beginning of exercise intervention and 1 day after the last training session in a fasting state. Results Six weeks of HIIT significantly increased the baseline serum levels of IL-4 (p = 0.022) and IL-13 (p = 0.014) in overweight adolescent boys. In addition, body weight (BW), BMI and body fat percent (BF%) were reduced in response to HIIT. Moreover, significantly negative correlations were found between changes of IL-4 and IL-13 with changes of BW, BMI and BF%. Conclusions HIIT seems to be an appropriate exercise modality for overweight adolescent boys to induce an anti-inflammatory cytokine response and, to improve body composition.

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Source
http://dx.doi.org/10.1515/hmbci-2019-0004DOI Listing

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