Nickel-catalyzed decarbonylation of -acylated N-heteroarenes is developed. This method can be used to produce a variety of -aryl heteroarenes, including pyrroles, indoles, carbazoles and phenoxazines, using benzoic acid derivatives as arylating reagents. Arylnickelamide intermediates that are relevant to the catalytic reaction were characterized by X-ray crystallography. When -acylated benzimidazoles are used as substrates, decarbonylation accompanied 1,2-migration to form 2-arylated benzimidazoles.
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| http://dx.doi.org/10.1039/c9sc02035g | DOI Listing |
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