Denosumab is a fully human monoclonal antibody which is used to treat osteoporosis and has been shown to cause hypocalcemia in patients with underlying prostatic and bone malignancies, renal impairment, postmenopausal state, and/or vitamin D deficiency. We present a case of a male patient, with a past medical history negative for the aforementioned conditions, who presented with right shoulder pain and was found to be severely hypocalcemic secondary to denosumab.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663059PMC
http://dx.doi.org/10.7759/cureus.4768DOI Listing

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