The evolutionary conservation of the catalytically inactive α-tryptase gene has remained a mystery. In this issue of , Le et al. (2019. https://doi.org/10.1084/jem.20190701) unveil the existence of a novel but natural tryptase, heteromeric α/β-tryptase, a critical mediator of α-tryptase-associated diseases.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780996 | PMC |
| http://dx.doi.org/10.1084/jem.20191169 | DOI Listing |
Publication Analysis
Top Keywords
alpha meets
4
meets beta
4
beta mast
4
mast cells
4
cells hyper
4
hyper evolutionary
4
evolutionary conservation
4
conservation catalytically
4
catalytically inactive
4
inactive α-tryptase
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!