The transversus thoracis muscle plane block (TTP) block is a newly developed regional anesthesia technique which provides analgesia to the anterior chest wall. Since its introduction, this technique has been utilized for a wide range of surgical procedures as well as nonsurgical indications. Current evidence suggests that the TTP block provides effective analgesia for breast and cardiac surgeries, cardiac device implantation, pericardiocentesis, and acute and chronic pain management. To date, no major complications have been reported. Currently there is an urgent need to standardize the nomenclature of this technique to facilitate accurate communication amongst care providers, researchers, and authors. In this review, we describe the TTP block technique, review the indications and available evidence in clinical practice, and discuss alternative blocks and future prospects.
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http://dx.doi.org/10.1155/2019/1716365 | DOI Listing |
Sci Bull (Beijing)
January 2025
State Key Laboratory of Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Chemistry, College of Chemistry and Chemical Engineering, Pen-Tung Sah Institute of Micro-Nano Science and Technology, Xiamen University, Xiamen 361005, China.
Despite the many advantages for industrial mass production, vacuum-deposited organic solar cells (OSCs) suffer from low efficiency, primarily due to the limited molecular library of small-molecule donor and acceptor materials, which remains a significant challenge. Herein, two donor-acceptor-acceptor (D-A-A)-configured small-molecule donors, named TTBTDC and TTBTDC-F were synthesized, using 8H-thieno[2',3':4,5]thieno[3,2-b]thieno[2,3-d]pyrrole (TTP) as a new fused-ring donor unit. Benefiting from the strong electron-donating ability of the TTP moiety and the adoption of the D-A-A molecular configuration, these molecules exhibited strong visible and near-infrared absorption as well as deep-lying highest occupied molecular orbital (HOMO) energy levels.
View Article and Find Full Text PDFPacing Clin Electrophysiol
January 2025
Service de rythmologie cardiaque, Hôpital Cardiologique Louis Pradel, Hospices Civils de Lyon, Lyon, France.
Background: Temporary transvenous pacing (TTP) is a common procedure, predominantly performed in the catheterization laboratory (cath lab) because of presumed lower complication rate. This study aims to evaluate the efficacy and safety of TTP placement in the ICU compared to TTP placement in the cath lab.
Methods: This retrospective, real-life study included all patients requiring TTP in a tertiary care ICU between 2019 and 2022.
Cell Res
February 2025
National Key Laboratory of Immunity & Inflammation, Second Military Medical University, Shanghai, China.
Immunometabolism is critical in the regulation of immunity and inflammation; however, the mechanism of preventing aberrant activation-induced immunopathology remains largely unclear. Here, we report that glyoxalase II (GLO2) in the glycolysis branching pathway is specifically downregulated by NF-κB signaling during innate immune activation via tristetraprolin (TTP)-mediated mRNA decay. As a result, its substrate S-D-lactoylglutathione (SLG) accumulates in the cytosol and directly induces D-lactyllysine modification of proteins.
View Article and Find Full Text PDFJ Thromb Haemost
December 2024
Department of Hematology, Nara Medical University, Kashihara, Japan; Department of Blood Transfusion Medicine, Nara Medical University, Kashihara, Japan. Electronic address:
J Microbiol Biotechnol
December 2024
Environmental Diseases Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Shiga toxins (Stxs), produced by serotype 1 and certain pathotypes, cause hemorrhagic colitis, which can progress to hemolytic uremic syndrome (HUS) and central nervous system (CNS) pathology. The underlying mechanisms of toxin-induced inflammation remain unclear. The p38 mitogen-activated protein kinase (MAPK) and its downstream target, MAPKAPK2 (MK2), play key roles in various cellular responses.
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