Relaxation oscillators are nonlinear electronic circuits that produce a repetitive non-sinusoidal waveform when sufficient voltage is applied. In this fashion, they are reminiscent of integrate-and-fire neuron models, except that they also include components with hysteresis, and thus require no threshold rule to determine when an impulse has occurred or to return the voltage to its reset value. Here, I discuss the pros and cons of teaching elementary neurophysiology using first-order linear integrate-and-fire neurons versus relaxation oscillator circuits. I suggest that the shortcomings of both types of models are useful in order to foster a critical understanding of the neurophysiology underlying the firing dynamics of biological neurons.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650253 | PMC |
Publication Analysis
Top Keywords
Similar Publications
An experimental EEG study of brain activities underlying the Autonomous Sensory Meridian Response.
IBRO Neurosci Rep
June 2025
Shiraz Neuroscience Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Autonomous Sensory Meridian Response (ASMR) is an audio-visual phenomenon that has recently become popular. Many people have reported experiencing a tingling-like sensation through their body while watching audio/video clips known as ASMR clips. People capable of having such experiences have also reported improved overall well-being and feeling relaxed.
View Article and Find Full Text PDFCartilaginous microtissues exhibit extreme resilience under compression with size-dependent mechanical properties.
Biomaterials
January 2025
Prometheus Division of Skeletal Tissue Engineering, KU Leuven, O&N1, Herestraat 49, PB 813, 3000, Leuven, Belgium; Skeletal Biology and Engineering Research, KU Leuven, ON1 Herestraat 49, PB 813, 3000, Leuven, Belgium. Electronic address:
Self-assembled cartilaginous microtissues provide a promising means of repairing challenging skeletal defects and connective tissues. However, despite their considerable promise in tissue engineering, the mechanical response of these engineered microtissues is not well understood. Here we examine the mechanical and viscoelastic response of progenitor cell aggregates formed from human primary periosteal cells and the resulting cartilaginous microtissues under large deformations as might be encountered in vivo.
View Article and Find Full Text PDFTemperature Areas of Local Inelasticity in Polyoxymethylene.
Polymers (Basel)
December 2024
Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences (IPCE RAS), Leninskiy Prospekt 31, 119071 Moscow, Russia.
The spectra of internal friction and temperature dependencies of the frequency of a free-damped oscillation process excited in the specimens of an amorphous-crystalline copolymer of polyoxymethylene with the co-monomer trioxane (POM-C) with a degree of crystallinity ~60% in the temperature range from -150 °C to +170 °C has been studied. It has been established that the spectra of internal friction show five local dissipative processes of varying intensity, manifested in different temperature ranges of the spectrum. An anomalous decrease in the frequency of the oscillatory process was detected in the temperature ranges where the most intense dissipative losses appear on the spectrum of internal friction.
View Article and Find Full Text PDFThe Posterior Dominant Rhythm Remains Within Normal Limits in the Microgravity Environment.
Brain Sci
November 2024
Brain.Space, Tel Aviv 58855, Israel.
Background: Electroencephalogram (EEG) biomarkers with adequate sensitivity and specificity to reflect the brain's health status can become indispensable for health monitoring during prolonged missions in space. The objective of our study was to assess whether the basic features of the posterior dominant rhythm (PDR) change under microgravity conditions compared to earth-based scalp EEG recordings.
Methods: Three crew members during the 16-day AXIOM-1 mission to the International Space Station (ISS), underwent scalp EEG recordings before, during, and after the mission by means of a dry-electrode self-donning headgear designed to support long-term EEG recordings in space.
Optomechanical micro-rheology of complex fluids at ultra-high frequency.
Nat Commun
January 2025
Matériaux et Phénomènes Quantiques, Université Paris Cité, CNRS UMR 7162, Paris, France.
We present an optomechanical method for locally measuring the rheological properties of complex fluids in the ultra-high frequency range (UHF). A mechanical disk of microscale volume is used as an oscillating probe that monitors a liquid at rest, while the oscillation is optomechanically transduced. An analytical model for fluid-structure interactions is used to deduce the rheological properties of the liquid.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!