Background: Debate on pricing and reimbursement of cancer medicines highlights the need to establish the value of cancer medicines.
Objective: This study aims to elicit the trade-offs in cancer medicine characteristics that the Belgian population is willing to make.
Methods: A discrete choice experiment used six attributes with three levels each, based on literature and focus group discussions. The survey was sent to a random sample of 3500 Belgian citizens. Based on the choice of 961 respondents, individual parameters were estimated with a mixed logit model.
Results: Societal value of cancer medicines was positively affected by a higher number of patients eligible for treatment, a high initial life expectancy and quality of life of patients, a high gain in quality of life and life expectancy due to treatment, and a low treatment cost. The value of 1-year gain in life expectancy was independent from the initial life expectancy of the patient. However, the value of one-point gain in quality of life was higher for patients with a low initial quality of life than for patients with a high initial quality of life.
Conclusions: This study has shown that gain in quality of life with cancer medicines is valued higher by Belgian society for patients who have lower initial quality of life before the start of treatment.
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http://dx.doi.org/10.1007/s40258-019-00504-4 | DOI Listing |
BMC Health Serv Res
January 2025
Division of Psychiatry, University College London, London, England.
Background: An increasing number of older people are experiencing homelessness and memory problems, many of whom are supported in temporary hostel accommodation. This can be a challenge for hostel staff who may not have adequate training and support but who often support those with significant memory impairment in their day-to-day work. The study aimed to investigate the training and support that hostel staff require to meet the needs of older hostel residents experiencing memory and cognitive problems, and thus enhance hostel resident quality of life and well-being, considering what additional knowledge, skills, and support hostel staff need to achieve this.
View Article and Find Full Text PDFArch Public Health
January 2025
School of Nursing and Midwifery, Medical-Surgical Nursing Department,, Tehran University of Medical Sciences, Tehran, Iran.
Background: ENABLE (Educate, Nurture, Advise, Before Life Ends) is a model of nurse-led, early palliative care that was originally developed for U.S. patients with advanced cancer and their family caregivers and then adapted for patients with heart failure.
View Article and Find Full Text PDFBMC Health Serv Res
January 2025
Department of Health Services Research, Faculty of Health, Medicine and Life Sciences, CAHPRI, Maastricht University Medical Center, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, the Netherlands.
Background: This study explores the facilitating and inhibiting factors in the design/development, implementation, and applicability/evaluation of value-based payment models of integrated care. The Delphi technique was used to reach consensus among a panel of (inter)national experts on these factors.
Methods: An expert panel of 15 members participated in a three-round Delphi study.
BMC Public Health
January 2025
Department of Public Health, Tzu Chi University, No.701, Sec. 3, Zhongyang Rd., Hualien County, Hualien City, 970, Taiwan.
Background: Humans experience functioning difficulties in daily life, which are dependent on the interaction between health conditions and barriers in life. In general, functioning is an umbrella term and a dynamic concept. Thus, identifying the factors associated with long-term functioning would be beneficial to the development of specific health policies and quality of life for people with disabilities.
View Article and Find Full Text PDFBMC Med
January 2025
Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.
Background: Inhaled corticosteroids (ICS) are recommended treatment for mild asthma. We aimed to update the evidence on the efficacy and safety of ICS-containing regimens, leukotriene receptor antagonists (LTRA), and tiotropium relative to as-needed (AN) short-acting β2-agonists (SABA) in children (aged 6-11 years) and adolescents/adults.
Methods: A systematic review of randomized controlled trials (RCTs) of regular and AN treatment for mild asthma was conducted (CRD42022352384).
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