A 72-year-old diabetic man was diagnosed with acute myocardial infarction of the anterior wall and underwent emergency off-pump coronary artery bypass grafting. He was diagnosed with ventricular septal perforation(VSP) 3 days after the operation. We urgently performed surgical repair of VSP with "extended sandwich patch technique through right ventriculotomy". There was no shunt recurrence. This technique is considered to offer safe, simple and leak-free repair even in an acute phase of VSP.
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RSC Adv
December 2024
Nanomedicine Laboratories, Center for Materials Science, Zewail City of Science and Technology 6th of October City Giza Egypt
Patients with rheumatoid arthritis (RA), an inflammatory illness that affects the synovial joints, have a much worse quality of life. Mostly, oral or injectable formulations are used to treat RA, underscoring the critical need for an innovative medication delivery method to enhance therapeutic outcomes and patient compliance. The present study integrated 3D bioprinting and electrospinning technologies to create a unique double-layered transdermal patch (TDDP) for the treatment of RA.
View Article and Find Full Text PDFKyobu Geka
October 2024
Department of Cardiovascular Surgery, Shiga University, Otsu, Japan.
An 86-year-old female was taken to hospital with complaints of general malaise and anorexia. Echocardiography showed an abnormal space between the ventricles, extending to the back of the left atrium, with a shunt from the left ventricle into both that abnormal space and the right ventricle. The next morning, the patient had a large amount of tarry stool and progressive anemia.
View Article and Find Full Text PDFNat Phys
October 2024
Dept. of Chemical Engineering, Stanford University, Palo Alto, CA USA.
During host infection, and related unicellular parasites move using gliding, which differs fundamentally from other known mechanisms of eukaryotic cell motility. Gliding is thought to be powered by a thin layer of flowing filamentous (F)-actin sandwiched between the plasma membrane and a myosin-covered inner membrane complex. How this surface actin layer drives the various gliding modes observed in experiments-helical, circular, twirling and patch, pendulum or rolling-is unclear.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
November 2024
The Second Rehabilitation Hospital of Shanghai, China; Engineering Research Center of Intelligent Rehabilitation for Traditional Chinese Medicine, Ministry of Education, School of Rehabilitation Science, Institute of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address:
Clinical cardiac patches exhibit unsatisfied biocompatibility, low adhesion, and inadequate compliance and suboptimal mechanical properties for cardiac disorders repair. To address these challenges, herein we have innovatively proposed a biomimetic nanofiber electrospun membrane with a sandwich structure strategy. The composite patch comprises a stretchable polyurethane (PU) as basic material, then infiltrated with biocompatible silk fibroin methacryloyl (Silk-MA) as the middle layer via electrospinning and finally covered with Bio-ILs (chemically modified biocompatible ionic liquids) to impart electrical conductivity.
View Article and Find Full Text PDFGen Thorac Cardiovasc Surg Cases
February 2024
Department of Cardiovascular Surgery, Isesaki Municipal Hospital, Isesaki, Gunma, 372-0817, Japan.
Background: Left ventricular pseudo-false aneurysm is a rare complication of myocardial infarction and generally caused by an intramyocardial dissecting hematoma due to a fragile myocardium. The serpiginous dissecting case of ventricular septal perforation has an entry port in the left ventricle and exit port in the right ventricle, and the entry port must be closed to leave the dissected chamber on the low-pressure right side for treatment. Herein, we report a case of a large left ventricular pseudo-false aneurysm that was unaccompanied by a shunt after the surgical repair of a ventricular septal dissection.
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