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Clinical Utility of Highly Purified 10% Liquid Intravenous Immunoglobulin in Kawasaki Disease. | LitMetric

AI Article Synopsis

  • A 10% intravenous immunoglobulin (IVIG) treatment for Kawasaki disease was more effective than a 5% IVIG, reducing fever duration among responders from 13 hours to 10 hours.
  • It also shortened the time to additional therapy for nonresponders from 49 hours to 47 hours.
  • The study found no severe adverse events related to the treatment.

Article Abstract

Compared with a 5% intravenous immunoglobulin, a 10% intravenous immunoglobulin as the first-line treatment of Kawasaki disease significantly reduced the fever duration (10 vs 13 hours, P = .022) among the responders, and the interval to adjunctive therapy for nonresponders (47 vs 49 hours, P = .035). There were no severe adverse events.

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Source
http://dx.doi.org/10.1016/j.jpeds.2019.06.018DOI Listing

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