Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/s40520-019-01284-6 | DOI Listing |
Alzheimers Dement
December 2024
NYU Grossman School of Medicine, New York, NY, USA.
Background: The lateral entorhinal cortex (LEC), followed by area CA1 of hippocampus, are interconnected brain areas implicated early in Alzheimer's disease (AD). Processing of LEC input by CA1 pyramidal neurons (PNs) is critical for non-spatial memory, in which deficits are seen in early AD. How this process is affected by tauopathy is unclear.
View Article and Find Full Text PDFJ Orthop Trauma
January 2025
Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD.
Objective: To determine whether bone transport or Masquelet results in higher rates of major unplanned reoperations for the treatment of segmental tibial bone defects ≥4 cm in length.
Methods: Design: Retrospective cohort.
Setting: Level I trauma center.
BMC Musculoskelet Disord
January 2025
Department of Geriatric Orthopedics, The Third Hospital of Hebei MedicalUniversity, No.139 ZiQiang Lu, Shijiazhuang, Hebei, 050051, PR China.
Background: Patients with preoperative acute heart failure (AHF) after hip fracture in the elderly have a worse prognosis. We aim to investigate the characteristics, risk factors and postoperative complications of elderly patients with hip fracture complicated with preoperative AHF. We also looked at the effect of the severity of anemia at admission on the prognosis of the above people.
View Article and Find Full Text PDFNat Commun
January 2025
Institute of Regenerative Biology and Medicine, Chinese Institutes for Medical Research, Beijing, China.
Lung fibrosis development utilizes alveolar macrophages, with mechanisms that are incompletely understood. Here, we fate map connective tissue during mouse lung fibrosis and observe disassembly and transfer of connective tissue macromolecules from pleuro-alveolar junctions (PAJs) into deep lung tissue, to activate fibroblasts and fibrosis. Disassembly and transfer of PAJ macromolecules into deep lung tissue occurs by alveolar macrophages, activating cysteine-type proteolysis on pleural mesothelium.
View Article and Find Full Text PDFJ Thromb Haemost
December 2024
Mayo Clinic, Cardiovascular Medicine - Gonda Vascular Center, Rochester, MN, United States. Electronic address:
Objectives: Study aims were to assess the impact of co-incident lower extremity (LE) deep vein thrombosis (DVT) on clinical outcomes of pulmonary embolism (PE) including venous thromboembolism (VTE) recurrence and mortality.
Methods: Consecutive patients with confirmed acute symptomatic or incidental PE (March 1, 2013 - June 30, 2021) who underwent ultrasound imaging were divided into two groups depending on the presence or absence of LE DVT. Patients were followed prospectively for VTE recurrence, bleeding, and all-cause mortality.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!