The discovery of the aggregation-induced emission (AIE) phenomenon in the early 2000s not only has overcome persistent challenges caused by traditional aggregation-caused quenching (ACQ), but also has brought about new opportunities for the development of useful functional molecules. Through the years, AIE luminogens (AIEgens) have been widely studied for applications in the areas of biomedical and biological sensing, chemosensing, optoelectronics, and stimuli responsive materials. Particularly in the application of chemosensing, a myriad of novel AIE-based sensors has been developed to detect different neutral molecular, cationic and anionic species, with a rapid detection time, high sensitivity and high selectivity by monitoring fluorescence changes. This review thus summarises the recent development of AIE-based chemosensors for the detection of anionic species, including halides and halide-containing anions, cyanides, and sulphur-, phosphorus- and nitrogen- containing anions, as well as a few other anionic species, such as citrate, lactate and anionic surfactants.
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http://dx.doi.org/10.3390/molecules24152711 | DOI Listing |
Nano Lett
January 2025
Disruptive & Sustainable Technologies for Agricultural Precision IRG, Singapore-MIT Alliance of Research and Technology, 1 CREATE Way, #03-06, Singapore 138602, Singapore.
Fluorescent nanosensors operating have shown recent success toward informing basic plant biology and agricultural applications. We developed near-infrared (NIR) fluorescent nanosensors using the Corona Phase Molecular Recognition (CoPhMoRe) technique that distinguish Fe(II) and Fe(III) species with limit of detection as low as 10 nM. An anionic poly(p-phenyleneethynylene) (PPE) polyelectrolyte wrapped single-walled carbon nanotube (SWNT) shows up to 200% turn-on and 85% turn-off responses to Fe(II) and Fe(III), respectively, allowing spatial and temporal analysis of iron uptake in both foliar and root-to-shoot pathways.
View Article and Find Full Text PDFChem Commun (Camb)
January 2025
Key Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, College of Chemistry, Sichuan University, Chengdu, 610064, China.
A macrocycle-based approach to the construction of a cationic polymeric network with pillar[5]arene as the node for efficient sequestration of hazardous IO and I is presented. Ultrafast kinetics ( 4 min) were achieved along with excellent adsorption capacities for both IO (456 mg g) and I (370 mg g), good selectivity, and outstanding reusability. This work showcases the merits of pillar[5]arene as nodes in cationic adsorption materials in the removal of anionic iodine species.
View Article and Find Full Text PDFToxicol Mech Methods
January 2025
Department of Pharmacology, SVKM's NMIMS School of Pharmacy and Technology Management, Babulde, Shirpur, 425405 Maharashtra, India.
Adverse drug reactions (ADR) remain a challenge in modern healthcare, particularly given the increasing complexity of therapeutics. WHO's definition of an adverse drug reaction as a response to a drug that is noxious and unintended and occurs at doses normally used in man for the prophylaxis, diagnosis or therapy of disease, or for modification of physiological function. This definition underscores the importance of monitoring and mitigating unintended drug effects, particularly for widely used medications like valproic acid (VPA).
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg 1, 8093 Zürich, Switzerland.
Organic redox systems that can undergo oxidative and reductive (ambipolar) electron transfer are elusive yet attractive for applications across synthetic chemistry and energy science. Specifically, the use of ambipolar redox systems in proton-coupled electron transfer (PCET) reactions is largely unexplored but could enable "switchable" reactivity wherein the uptake and release of hydrogen atoms are controlled using a redox stimulus. Here, we describe the synthesis and characterization of an ambipolar functionalized terthiophene (TTH) bearing methyl thioether and phosphine oxide groups that exhibits switchable PCET reactivity.
View Article and Find Full Text PDFPLoS One
January 2025
Institute of Natural Antioxidants and Anti-Inflammation, Dali University, Dali, Yunnan, China.
Oxidative damage, oxidative inflammation, and a range of downstream diseases represent significant threats to human health. The application of natural antioxidants and anti-inflammatory agents can help prevent and mitigate these associated diseases. In this study, we aimed to investigate the effectiveness of walnut green husk (WNGH) as an antioxidant and anti-inflammatory agent in an in vitro setting.
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