Nowadays, medical informatics is unavoidable topic when talking about health innovations and modern practice. Education of professionals in medical informatics is a challenging issue since they need to be capable to respond to challenges of modern health care systems, heterogeneous health information systems with integrated devices and remote access/controls, rapid development of both technology and the character of applications, etc. However, variety of medical informatics educational programs are established all over the world, and there is no general approach that shall be followed and applied. This paper presents key findings and results of comprehensive review and analyses of well-known EU best practices in medical informatics education, on which bases innovative star model is created for educational system in medical informatics at national level.
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http://dx.doi.org/10.3233/SHTI190046 | DOI Listing |
Neuroradiology
January 2025
Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Introduction: Bipolar disorder (BD) and major depressive disorder (MDD) have overlapping clinical presentations which may make it difficult for clinicians to distinguish them potentially resulting in misdiagnosis. This study combined structural MRI and machine learning techniques to determine whether regional morphological differences could distinguish patients with BD and MDD.
Methods: A total of 123 participants, including BD (n = 31), MDD (n = 48), and healthy controls (HC, n = 44), underwent high-resolution 3D T1-weighted imaging.
J Coll Physicians Surg Pak
January 2025
Anti-Quackery Committee, Sindh Healthcare Commission, Karachi, Pakistan.
Fraudulent medical practices remain prevalent globally, fueled by digital platforms spreading false claims. This study analysed 3,327 published studies and 400 grey literature sources, selecting 38 studies and 19 excerpts for detailed examination. It identified 126 distinct quackery techniques and products used throughout history.
View Article and Find Full Text PDFJ Coll Physicians Surg Pak
January 2025
Department of Radiation Oncology, CyberKnife and Tomotherapy Centre, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.
Objective: To assess the disease response and patient survival outcomes for cancer patients treated with helical tomotherapy.
Study Design: Descriptive study. Place and Duration of the Study: The Tomotherapy Unit of Jinnah Postgraduate Medical Centre, Karachi, Pakistan, from October 2020 to August 2023.
Hum Genomics
January 2025
Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Richards Building B304, 3700 Hamilton Walk, Philadelphia, PA, 19104, USA.
Background: Disease comorbidities and longer-term complications, arising from biologically related associations across phenotypes, can lead to increased risk of severe health outcomes. Given that many diseases exhibit sex-specific differences in their genetics, our objective was to determine whether genotype-by-sex (GxS) interactions similarly influence cross-phenotype associations. Through comparison of sex-stratified disease-disease networks (DDNs)-where nodes represent diseases and edges represent their relationships-we investigate sex differences in patterns of polygenicity and pleiotropy between diseases.
View Article and Find Full Text PDFRadiat Oncol
January 2025
Department of Radiation Oncology, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, 300060, China.
Background: Several studies have suggested that lung tissue heterogeneity is associated with overall survival (OS) in lung cancer. However, the quantitative relationship between the two remains unknown. The purpose of this study is to investigate the prognostic value of whole lung-based and tumor-based radiomics for OS in LA-NSCLC treated with definitive radiotherapy.
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