Multifunctional one-dimensional polymeric nanostructures for drug delivery and biosensor applications.

Nanotechnology

Materials Science and Nano Engineering, Faculty of Engineering and Natural Sciences, Sabanci University, 34956 Istanbul, Turkey.

Published: October 2019

AI Article Synopsis

  • Recent advances in nanotechnology have led to major breakthroughs in the diagnosis and treatment of diseases, especially through the use of various functional nanostructures.
  • One-dimensional nanostructures, due to their higher surface area-to-volume ratios, are particularly promising for theranostic applications, enhancing targeting and sensitivity.
  • The review discusses different synthesis techniques for these polymeric nanostructures, their functionalization for specific uses, and highlights their roles in biosensing and drug delivery.

Article Abstract

Advances in nanotechnology in the last decades have paved the way for significant achievements in diagnosis and treatment of various diseases. Different types of functional nanostructures have been explored and utilized as tools for addressing the challenges in detection or treatment of diseases. In particular, one-dimensional nanostructures hold great promise in theranostic applications due to their increased surface area-to-volume ratios, which allow better targeting, increased loading capacity and improved sensitivity to biomolecules. Stable polymeric nanostructures that are stimuli-responsive, biocompatible and biodegradable are especially preferred for bioapplications. In this review, different synthesis techniques of polymeric one-dimensional nanostructures are explored and functionalization methods of these nanostructures for specific applications are explained. Biosensing and drug delibiovery applications of these nanostructures are presented in detail.

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http://dx.doi.org/10.1088/1361-6528/ab2e2cDOI Listing

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