Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/13506129.2019.1582485 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Therapeutic Efficacy of the Inositol D-Pinitol as a Multi-Faceted Disease Modifier in the 5×FAD Humanized Mouse Model of Alzheimer's Amyloidosis.
Nutrients
December 2024
Grupo de Neuropsicofarmacología, Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, Unidades Clínicas de Neurología y Salud Mental, 29010 Málaga, Spain.
Background/objectives: Alzheimer's disease (AD), a leading cause of dementia, lacks effective long-term treatments. Current therapies offer temporary relief or fail to halt its progression and are often inaccessible due to cost. AD involves multiple pathological processes, including amyloid beta (Aβ) deposition, insulin resistance, tau protein hyperphosphorylation, and systemic inflammation accelerated by gut microbiota dysbiosis originating from a leaky gut.
View Article and Find Full Text PDFComparison between Immunoglobulin G4-Related Eye Disease and Other Entities with Non-Immunoglobulin G4 Ocular Involvement.
Eur J Rheumatol
July 2024
Department of Rheumatology, Hospital J.M. Cullen, Santa Fe, Argentina.
Article Synopsis
- The study aimed to differentiate IgG4-related ocular disease (IgG4-ROD) from non-IgG4 ocular diseases by examining various clinical and analytical features.
- It involved 18 patients with IgG4-ROD and 12 with other inflammatory or autoimmune conditions, comparing demographic profiles and symptoms like proptosis and diplopia.
- Results showed a higher prevalence of specific symptoms like proptosis and xerophthalmia in IgG4-ROD, with significant associations found between certain features and the disease type.
What's new in cardiac amyloidosis? Pharmacological treatment, physical activity, and care of patients with transthyretin cardiac amyloidosis.
Ther Adv Cardiovasc Dis
November 2024
Cardiovascular Pharmacology Research Group, Department of Pharmacology and Toxicology, Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Awareness, proper diagnosis and treatment of cardiac amyloidosis have increased, but there are still several unmet needs that have to be addressed for the optimal care of the disease. In this comprehensive review, we describe current and future treatments for both hereditary and wild-type TTR cardiac amyloidosis and also review lifestyle, including current challenges and opportunities for specific dietary concerns and exercise sports for these patients.
View Article and Find Full Text PDF[Prevalence of transthyretin cardiac amyloidosis in patients hospitalized for heart failure with preserved ejection fraction and septal thickness].
Medicina (B Aires)
October 2024
Servicio de Cardiología, Hospital Italiano de Buenos Aires, Argentina.
Article Synopsis
- * A cross-sectional approach was employed, analyzing patients over 18 with specific heart failure criteria, and a pyrophosphate bone scintigraphy (PYP) was used to diagnose ATTR-CM.
- * Results showed that 19% of the patients tested positive for ATTR-CM, indicating it's a significant concern among this population and suggesting that routine screening for the condition is warranted.
Atrial fibrillation in transthyretin amyloidotic cardiomyopathy: prevalence and echocardiographic predictors.
Minerva Cardiol Angiol
October 2024
Unit of Cardiology, Department of Cardiology, Cardiovascular Institute of Buenos Aires, Buenos Aires, Argentina.
Background: Conduction disorders and arrhythmias frequently accompany cardiac amyloidosis (CA), with atrial fibrillation (AF) being the most prevalent manifestation. The prevalence of AF varies across different types of CA, with transthyretin (TTR) type showing the highest prevalence upon diagnosis.
Methods: A retrospective, observational analysis was conducted to evaluate the prevalence of AF and to identify echocardiographic predictors related to the development of AF in our population of patients with transthyretin cardiac amyloidosis (TTR-CA).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!