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http://dx.doi.org/10.1080/13506129.2019.1582024 | DOI Listing |
J Am Soc Echocardiogr
December 2024
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN; Mayo Clinic School of Medicine, Mayo Clinic College of Medicine and Science, Mayo Clinic, Rochester, MN.
Exercise intolerance is a hallmark symptom in adults with repaired tetralogy of Fallot (TOF). This may be attributed to the disease-related impairment in RV systolic function, augmentation in right ventricular (RV) load, and their combined effect on altering left ventricular (LV) hemodynamics. To further elucidate these mechanisms, we examined oxygen uptake (VO) by indirect-calorimetry and cardiac hemodynamics by echocardiography in 34 TOF (48 ± 14 yrs) and 29 healthy controls (41 ± 15 yrs), at rest and during exercise.
View Article and Find Full Text PDFClin J Am Soc Nephrol
December 2024
Department of Nephrology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Background: Potential impairment of exercise capacity is prevalent even in patients undergoing hemodialysis without frailty. Cardiopulmonary exercise testing (CPET) can detect physiological reserves such as cardiopulmonary, muscle, and autonomic function. We hypothesized that these indices could accurately determine the prognosis of patients on hemodialysis and analyzed them based on their relationship to frailty.
View Article and Find Full Text PDFHeart Fail Rev
December 2024
Institute of Heart Diseases, University Hospital in Wrocław, Wrocław Medical University, Wrocław, Poland.
Clin Res Cardiol
November 2024
Department of Cardiovascular Medicine, Kyorin University Hospital, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan.
Backgrounds: Heart rate (HR) and stroke volume (SV)-the components of cardiac output-have a complementary relationship. Poor HR increase during exercise is associated with poor exercise tolerance in heart failure (HF) with preserved ejection fraction (HFpEF), but its prognostic impact remains unclear. Furthermore, whether the compensation for poor HR increase with SV during exercise is associated with prognosis remains unknown.
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