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Prognostic Value of Dynamic Measurable Residual Disease Monitoring by Multiflowcytometry in Elderly Patients With Nonintensively Treated Acute Myeloid Leukemia.
Clin Lymphoma Myeloma Leuk
January 2025
Department of Hematology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China. Electronic address:
Purpose: The clinical prognostic value of monitoring minimal residual disease (MRD) in acute myeloid leukemia (AML) patients undergoing nonintensive treatment remains insufficiently established. The aim of this work was to examine MRD status at various time points, highlighting the potential for pre-emptive therapy to improve patient outcomes.
Methods: Inpatient data from 2017 to 2024 were used in this retrospective study.
Nanolabels for biosensors based on lateral flow immunoassays.
Anal Chim Acta
February 2025
Department of Physical and Analytical Chemistry & Institute of Biotechnology of Asturias, University of Oviedo, c/Julián Clavería 8, 33006, Oviedo, Spain. Electronic address:
The COVID-19 outbreak was an important turning point in the development of a new generation of biosensing technologies. The synergistic combination of an immunochromatographic test (lateral flow immunoassays, LFIA) and signal transducers provides enhanced sensitivity and the ability to quantify in the rapid tests. This is possible due to the variety of nanoparticles that can be used as reporter labels.
View Article and Find Full Text PDFParenthood, gender, and turning points to crime for young people in Latin America.
Adv Life Course Res
January 2025
Department of Political Science and Public Law, Autonomous University of Barcelona, Cerdanyola del Vallès, Bellaterra 08193, Spain.
In very different societal contexts, parenthood has been identified as a critical turning point in life course trajectories. In this qualitative study, we explore parenthood as a turning point for 40 young women and 40 young men in prisons across Latin America. We study the impact of parenthood on criminal trajectories, identify gender differences, and analyze the different mechanisms at work.
View Article and Find Full Text PDFExplainable AI in Diagnostic Radiology for Neurological Disorders: A Systematic Review, and What Doctors Think About It.
Diagnostics (Basel)
January 2025
Aerospace Engineering Department and Interdisciplinary Research Center for Smart Mobility and Logistics, and Interdisciplinary Research Center Aviation and Space Exploration, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia.
Artificial intelligence (AI) has recently made unprecedented contributions in every walk of life, but it has not been able to work its way into diagnostic medicine and standard clinical practice yet. Although data scientists, researchers, and medical experts have been working in the direction of designing and developing computer aided diagnosis (CAD) tools to serve as assistants to doctors, their large-scale adoption and integration into the healthcare system still seems far-fetched. Diagnostic radiology is no exception.
View Article and Find Full Text PDFStudy of the Interplay Among Melt Morphology, Rheology and 3D Printability of Poly(Lactic Acid)/Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) Blends.
J Funct Biomater
January 2025
Department of Chemistry, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.
Polymeric materials made from renewable sources that can biodegrade in the environment are attracting considerable attention as substitutes for petroleum-based polymers in many fields, including additive manufacturing and, in particular, Fused Deposition Modelling (FDM). Among the others, poly(hydroxyalkanoates) (PHAs) hold significant potential as candidates for FDM since they meet the sustainability and biodegradability standards mentioned above. However, the most utilised PHA, consisting of the poly(hydroxybutyrate) (PHB) homopolymer, has a high degree of crystallinity and low thermal stability near the melting point.
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