We present a series of SIR-network models, extended with a game-theoretic treatment of imitation dynamics which result from regular population mobility across residential and work areas and the ensuing interactions. Each considered SIR-network model captures a class of vaccination behaviours influenced by epidemic characteristics, interaction topology, and imitation dynamics. Our focus is the resultant vaccination coverage, produced under voluntary vaccination schemes, in response to these varying factors. Using the next generation matrix method, we analytically derive and compare expressions for the basic reproduction number R 0 for the proposed SIR-network models. Furthermore, we simulate the epidemic dynamics over time for the considered models, and show that if individuals are sufficiently responsive towards the changes in the disease prevalence, then the more expansive travelling patterns encourage convergence to the endemic, mixed equilibria. On the contrary, if individuals are insensitive to changes in the disease prevalence, we find that they tend to remain unvaccinated. Our results concur with earlier studies in showing that residents from highly connected residential areas are more likely to get vaccinated. We also show that the existence of the individuals committed to receiving vaccination reduces R 0 and delays the disease prevalence, and thus is essential to containing epidemics.
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http://dx.doi.org/10.3390/ijerph16142477 | DOI Listing |
Biomimetics (Basel)
December 2024
School of Computer Science and Technology, Dongguan University of Technology, Dongguan 523808, China.
In this paper, a deep reinforcement learning (DRL) approach based on generative adversarial imitation learning (GAIL) and long short-term memory (LSTM) is proposed to resolve tracking control problems for robotic manipulators with saturation constraints and random disturbances, without learning the dynamic and kinematic model of the manipulator. Specifically, it limits the torque and joint angle to a certain range. Firstly, in order to cope with the instability problem during training and obtain a stability policy, soft actor-critic (SAC) and LSTM are combined.
View Article and Find Full Text PDFCurr Res Food Sci
December 2024
Ottawa Laboratory (Carling), Canadian Food Inspection Agency, Ottawa, Ontario, Canada.
Towards fostering a more sustainable food production system in face of the climate change challenge, alternative protein meat-substitute products that are plant-based and free of animal by-products have been gaining attractions from both food manufacturers and consumers. With these so-called plant-based meat analogues (PBMAs) becoming increasingly available at supermarkets, there is very little known about their microbial properties. In this short report, we characterized the bacterial composition of raw plant-based ground meat imitation retail products using 16S rRNA gene amplicon sequencing.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
Department of Mechanical Engineering, University of California, Santa Barbara, Santa Barbara, California 93106, United States.
Controlling cellular shape with micropatterning extracellular matrix (ECM) proteins on hydrogels has been shown to improve the reproducibility of the cell structure, enhancing our ability to collect statistics on single-cell behaviors. Patterning methods have advanced efforts in developing human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) as a promising human model for studies of the heart structure, function, and disease. Patterned single hiPSC-CMs have exhibited phenotypes closer to mature, primary CMs across several metrics, including sarcomere alignment and contractility, area and aspect ratio, and force production.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
December 2024
Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC, Leiden, The, Netherlands.
The mobility of proteins in the bilayer membrane is affected by (local) changes in lipid environment, which is important to their biological functioning. Artificial molecular systems that-to some extent-imitate tasks of membrane-embedded proteins are increasingly developed, however, they are usually controlled through responsive units in their core structure. Here we present an alternative approach based on an amphiphilic stiff-stilbene derivative that enables control of membrane fluidity by light.
View Article and Find Full Text PDFNeural Netw
November 2024
Institute of Physics, Saratov State University, 83 Astrakhanskaya str., 410012 Saratov, Russia. Electronic address:
The widespread development and use of neural networks have significantly enriched a wide range of computer algorithms and promise higher speed at lower cost. However, the imitation of neural networks by means of modern computing substrates is highly inefficient, whereas physical realization of large scale networks remains challenging. Fortunately, delayed-feedback oscillators, being much easier to realize experimentally, represent promising candidates for the empirical implementation of neural networks and next generation computing architectures.
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