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Multiple Central Nervous System Cryptococcomas Masquerading as Lymphoma.
Neurohospitalist
December 2024
Department of Neurology, TriStar Centennial Medical Center, Nashville, TN, USA.
Cryptococcal meningitis is a leading cause of morbidity and mortality in patients infected with human immunodeficiency virus. In over 90% of cases, it occurs at CD4 T lymphocyte (CD4) cell counts of less than 100 cells/mm. Cryptococcomas are rare granulomatous lesions that can occur in disseminated central nervous system cryptococcal infection, primarily in immunocompetent hosts.
View Article and Find Full Text PDFA case of immunocompetent intracranial cryptococcoma in which intraoperative rapid pathological diagnosis and polymerase chain reaction led to early treatment: What to know to avoid misdiagnosis as brain tumor.
Surg Neurol Int
September 2024
Department of Neurosurgery, Ehime University School of Medicine, Toon, Ehime, Japan.
Article Synopsis
- * Patient symptoms included fever, headache, and hearing loss, with tests revealing infection indicators and abnormal brain lesions confirmed through advanced imaging techniques.
- * Rapid pathological diagnosis, including immunohistochemistry and PCR, played a vital role in distinguishing the cryptococcoma from a potential malignant tumor, leading to successful antifungal treatment.
Cryptococcoma in an immunocompetent patient: Unveiling the mystery of a rare rim-enhancing brain lesion.
Radiol Case Rep
December 2024
Department-Infectious Diseases, Staten Island University Hospital, Northwell Health, Staten Island, NY, USA.
A 59-year-old immunocompetent male who initially presented with symptoms of stroke was found to have an incidental rim-enhancing lesion on magnetic resonance imaging (MRI) of the brain. This discovery led to a lumbar puncture to analyze the cerebrospinal fluid, resulting in the diagnosis of cryptococcoma. The patient was subsequently managed with liposomal amphotericin B, followed by consolidation and maintenance therapy with fluconazole.
View Article and Find Full Text PDFDisseminated cerebral cryptococcoma mimicking glioblastoma - A case report.".
Indian J Med Microbiol
June 2024
Department of Neuromicrobiology, NIMHANS, Bengaluru, 29, India. Electronic address:
We discuss a rare instance of cryptococcoma caused by Cryptococcus gattii in a 55-year-old woman initially treated for suspected COVID bronchopneumonia. The diagnosis posed a challenge due to vague symptoms and unclear imaging findings suggesting malignancy. Postoperative samples confirmed the presence of Cryptococcus gattii through culture of brain tissue and blood.
View Article and Find Full Text PDF[Pituitary cryptococcoma: a strange case of secondary granulomatous hypophysitis].
Medicina (B Aires)
December 2023
Servicio de Clínica Médica, Instituto de investigaciones Médicas Alfredo Lanari, Buenos Aires, Argentina.
Hypophysitis is a pathology with low incidence and prevalence. Likewise, deep fungal infections in immunocompetent patients also represent a rare phenomenon. Even rarer is the case described below, where these two mentioned elements are combined, namely: pituitary cryptococcoma or granulomatous hypophysitis caused by said pathogen in a host without altered immune response.
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