To determine whether some of the side effects of antiepileptic drugs could be due to zinc depletion within tissues, zinc concentrations in the polymorphonuclear leucocytes in 26 epileptic patients receiving valproate or carbamazepine and 14 controls were assessed. There was no difference in zinc concentration in leucocytes among the three groups and no evidence of zinc depletion. Valproate and carbamazepine may affect the intracellular distribution of zinc.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1141510 | PMC |
| http://dx.doi.org/10.1136/jcp.41.5.553 | DOI Listing |
Publication Analysis
Top Keywords
zinc concentrations
8
patients receiving
8
antiepileptic drugs
8
zinc depletion
8
valproate carbamazepine
8
zinc
6
concentrations leucocytes
4
leucocytes patients
4
receiving antiepileptic
4
drugs determine
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!