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Norfloxacin Fluorescent Probe for the Assessment of Cefepime in Biological Fluids and Pharmaceutical Formulation; Investigation of the Greenness and Blueness Characteristics.
Luminescence
January 2025
Department of Chemistry, College of Science, Jouf University, Sakaka, Aljouf, Saudi Arabia.
In the present study, a norfloxacin (NFX) fluorescent probe was tailored for the spectrofluorometric measurement of cefepime (CFP). The proposed approach measured the quenching effect of CFP on the fluorescence intensity of NFX in acetate buffer solution. The obtained results show that CFP strongly quenches the fluorescence of NFX in a static mechanism.
View Article and Find Full Text PDFMaternal mental disorders, psychotropic drugs, socioeconomic status, and offspring congenital anomalies.
J Int Med Res
January 2025
Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Objective: To evaluate whether there is an association between maternal mental health, purchase of psychotropic drugs, socioeconomic status and major congenital anomalies in offspring.
Methods: A register-based cohort study of 6189 Finnish primiparous women who had a singleton delivery between 2009 and 2015. Data on pregnancy and delivery outcomes, psychiatric diagnosis, prescription drug purchases and offspring congenital anomalies were obtained from Finnish national registers.
Delineating CYP2C19-Mediated Interactions: Network Pharmacology Investigation of Ilaprazole and Clopidogrel versus Conventional Proton Pump Inhibitors.
Curr Drug Discov Technol
December 2024
Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu District, Tamilnadu, 603203, India.
Background: Clopidogrel, an antiplatelet drug commonly used in cardiovascular disease, is metabolized by the liver mainly through CYP2C19. Concomitant use of Proton pump inhibitors along with clopidogrel may affect the potency of clopidogrel by CYP2C19 inhibition. However, a novel PPI, ilaprazole is known to differ in its pharmacokinetic features, given the potential differences between ilaprazole's interactions and their metabolism with clopidogrel.
View Article and Find Full Text PDFFacilitators and Barriers to COVID-19 Vaccine Uptake Among Meat Processing Workers in Nebraska: A Mixed-Methods Analysis Using the COM-B Model.
Health Promot Pract
January 2025
University of Nebraska Medical Center, Omaha, NE, USA.
The meat processing industry was significantly impacted by the COVID-19 pandemic. Deemed essential, the meat processing workforce faced the risk of exposure to the SARS-CoV-2 virus. Along with other essential workforces, meat processing workers were prioritized in the national approach to receive COVID-19 vaccines by the Centers for Disease Control and Prevention Advisory Committee on Immunization Practices.
View Article and Find Full Text PDFBeyond anxiety: Autonomy and harm reduction approaches to DIY Hormone Replacement Therapy.
Indian J Med Ethics
January 2025
Assistant Professor of Practice, Centre for Writing & Pedagogy, Krea University; Working Editor, Indian Journal of Medical Ethics, INDIA.
A researcher in a Hyderabad-based science institution, Roshni (name changed to preserve anonymity) started identifying as a transgender woman in 2018, and wanted to start her medical transition - the process by which transgender people seek to affirm and express their gender using medical interventions.
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