Calodioscurins A and B, two new isoprenylated xanthones from the stem bark of P.F. Stevens.

Nat Prod Res

Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya, Indonesia.

Published: April 2021

Two new isoprenylated xanthones, calodioscurin A () and B () were isolated from the stem bark of P.F. Stevens along with two known isoprenylated 4-phenylcoumarins, apetalolide () and methyl inophyllum P (). The structures of two new compounds were determined based on their HRESIMS, IR, UV, 1D and 2D NMR spectral data. Compounds - were assayed on P-388 cells, compound showed IC value 11.5 μM and categorised moderate activity.

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http://dx.doi.org/10.1080/14786419.2019.1643864DOI Listing

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