We report a case of severe babesiosis caused by the bovine pathogen Babesia divergens with the development of multisystem failure in a splenic host. Immunosuppression other than splenectomy can also predispose people to B. divergens. There was heavy multiple invasion of up to 14 parasites inside the erythrocyte, which had not been previously observed even in asplenic hosts. The piroplasm 18S rRNA sequence from our patient was identical B. divergens EU lineage with identity 99.5-100%.
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http://dx.doi.org/10.1016/j.ttbdis.2019.07.006 | DOI Listing |
Bioinform Biol Insights
December 2024
Discipline of Genetics, School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa.
Objective: Babesiosis is a significant haemoparasitic infection caused by apicomplexan parasites of the genus . This infection has continuously threatened cattle farmers owing to its devastating effects on productivity and severe economic implications. Failure to curb the increase of the infection has been attributed to largely ineffective vaccines.
View Article and Find Full Text PDFPLoS Negl Trop Dis
December 2024
Department of Parasitology, Faculty of Veterinary Medicine, University of Fırat, Elazig, Turkey.
Small ruminant babesiosis remains a neglected disease despite causing significant economic losses to sheep and goat herds in many regions around the world. The pathogenesis and clinical manifestations of ovine babesiosis are well-known, but there is a lack of information regarding caprine babesiosis. Since the discovery of the first Babesia spp.
View Article and Find Full Text PDFFront Cell Infect Microbiol
November 2024
Department of Parasitology, Faculty of Veterinary Medicine, University of Firat, Elazig, Türkiye.
, commonly associated with ovine babesiosis, poses a significant threat to sheep health, often resulting in severe clinical manifestations and high mortality rates. However, the impact of on goats has remained uncertain, prompting us to investigate its pathogenicity in caprine hosts. Experimental infections using -infected blood inoculation and infected tick infestation, were conducted on spleen-intact (n=5) and splenectomized (n=5) goats.
View Article and Find Full Text PDFPLoS Pathog
November 2024
National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.
Infect Genet Evol
November 2024
Division of Parasitology, ICAR- Indian Veterinary Research Institute, Izatnagar, Bareilly 243122, Uttar Pradesh, India.
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