AI Article Synopsis

  • - Kratom is a psychoactive herb that acts as a stimulant in low doses and mimics opioids in higher doses, traditionally used in southeast Asia but gaining popularity in Western countries as an opioid substitute.
  • - The FDA has not restricted kratom due to challenges in isolating its adverse effects from those of other substances, even though increasing cases of use are reported.
  • - A case study of a 35-year-old man who experienced cardiac arrest solely from kratom illustrates its potential severe health risks, emphasizing the urgent need for regulation and caution in its use.

Article Abstract

Kratom is a psychoactive herb that has stimulant properties at low doses and has opioid-like properties at higher doses. It has been used for centuries in southeast Asia as a stimulant but has gained increasing popularity as a substitute for opioids in western countries as it is easily available. As most cases of kratom use involve other drugs too, the Food and Drug Administration (FDA) has stopped short of restricting kratom due to difficulty in assessing the adverse effects of kratom alone. We present the case of a young healthy 35-year-old man who suffered a cardiac arrest due to kratom use with no other coingestants. He was subsequently intubated and found to have systolic dysfunction and small brain infarcts. Fortunately, he made a successful recovery and was discharged after a stay at thebehavioural health centre. Our case highlights the potential adverse effects of kratom and the need to regulate its use.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663180PMC
http://dx.doi.org/10.1136/bcr-2019-229778DOI Listing

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