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Mediation of the effect of prenatal maternal smoking on time to natural menopause in daughters by birthweight-for-gestational-age z-score and breastfeeding duration: analysis of two UK birth cohorts born in 1958 and 1970.
BMC Womens Health
January 2025
School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.
Background: Prenatal maternal smoking, lower birthweight, and shorter breastfeeding duration have all been associated with an earlier age at menopause in daughters. We estimated the extent to which birthweight-for-gestational-age z-score and breastfeeding duration mediate the effect of prenatal maternal smoking on time to natural menopause in daughters.
Methods: Using pooled data from two prospective birth cohort studies - the 1970 British Cohort Study (n = 3,878) followed-up to age 46 years and the 1958 National Child Development Study (n = 4,822) followed-up to age 50 years - we perform mediation analysis with inverse odds weighting implemented in Cox proportional-hazards models.
Harmony in healthcare: recommended infant feeding practices and associated factors among HIV positive mothers in Eastern Ethiopian hospitals.
J Health Popul Nutr
January 2025
Department of Health Promotion, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Background: For mothers identified as HIV-infected, recommended infant feeding practices must prioritize the highest likelihood of ensuring HIV-free survival for their children while preserving maternal health. Consequently, understanding the feeding status during critical infancy stages, especially under the risk of HIV, plays a crucial role in enhancing the quality of life within this specific population segment. Hence, this study was conducted to assess the magnitude and associated factors of recommended infant feeding practices and its associated factors among HIV-positive mothers in Eastern Ethiopian Hospitals.
View Article and Find Full Text PDFImpact of maternal and offspring smoking and breastfeeding on oesophageal cancer in adult offspring.
Nat Commun
January 2025
Department of Radiation Therapy, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China.
Numerous risk factors for oesophageal cancer are linked to lifestyle habits, but the role of early-life factors in its incidence and mortality is unclear. Using UK Biobank data, we explore the association among breastfeeding, maternal smoking, smoking in offspring, and oesophageal cancer risk in adult offspring via multivariable Cox regression. Here, we show that being breastfed, compared with not being breastfed, is associated with a lower risk of oesophageal cancer incidence (HR: 0.
View Article and Find Full Text PDFDysbiosis of infant gut microbiota is related to the altered fatty acid composition of human milk from mothers with gestational diabetes mellitus: a prospective cohort study.
Gut Microbes
December 2025
School of Public Health, Qingdao University, Qingdao, China.
Gestational diabetes mellitus (GDM) is known to be associated with dysbiosis of offspring gut microbiota, but the mechanism remains unclear. The present prospective study explored the role of human milk fatty acid composition in this association. Mothers with GDM and normal controls were recruited at 24-28 gestational weeks.
View Article and Find Full Text PDFBreastfeeding empowerment and its relationship with health literacy and spousal support among breastfeeding mothers in Tabriz, Iran: a cross-sectional study.
BMJ Open
January 2025
Department of Psychiatry, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: Breast milk is crucial for the health and survival of infants, but exclusive breastfeeding often fails due to various reasons such as lack of breastfeeding empowerment.
Objectives: This study aimed to determine the status of breastfeeding empowerment and its relationship with health literacy and perceived spousal support among breastfeeding mothers while recognising that other related factors also contribute to breastfeeding empowerment.
Design: Cross-sectional study.
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