Content-aware image restoration for electron microscopy.

Methods Cell Biol

Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Center for Systems Biology Dresden (CSBD), Dresden, Germany. Electronic address:

Published: April 2020

Multiple approaches to use deep neural networks for image restoration have recently been proposed. Training such networks requires well registered pairs of high and low-quality images. While this is easily achievable for many imaging modalities, e.g., fluorescence light microscopy, for others it is not. Here we summarize on a number of recent developments in the fast-paced field of Content-Aware Image Restoration (CARE), in particular, and the associated area of neural network training, more in general. We then give specific examples how electron microscopy data can benefit from these new technologies.

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http://dx.doi.org/10.1016/bs.mcb.2019.05.001DOI Listing

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