Synthetic analogues of marine cytotoxic jaspine B and its stereoisomers.

Synthetic analogues of the cytotoxic jaspine B and its stereochemical congeners have become an attractive target in the synthetic organic community owing to the search for novel therapeutic candidates with more potent anticancer activity, as cancer is the second leading cause of death worldwide. This review article provides insights into the different approaches and strategies available in the literature for the construction of jaspine B-related compounds.