In this issue of Cell Chemical Biology, Plate et al. (2019) used quantitative interactome proteomics to define the molecular mechanism by which ATF6 activation reduces amyloidogenic protein secretion. These results shed light on preventing the amyloid formation at the very early step to treat devastating amyloid diseases.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102898 | PMC |
| http://dx.doi.org/10.1016/j.chembiol.2019.07.003 | DOI Listing |
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