Wound healing complications in oncological patients: perspectives for cellular therapy.

Postepy Dermatol Alergol

Department of Clinical Immunology and Transplantology, Medical University of Gdansk, Gdansk, Poland.

Published: April 2019

AI Article Synopsis

  • Cancer poses significant medical and social challenges, with traditional treatments like chemotherapy and radiotherapy being the main approaches.
  • These therapies often lead to serious side effects, particularly affecting rapidly dividing skin and immune cells, which complicates wound healing.
  • To enhance wound healing for cancer patients, various strategies are being explored, including specialized dressings, biomaterials, growth factors, and cell therapies.

Article Abstract

Various types of cancer are nowadays a serious medical and social problem and a great challenge for modern medicine. The majority of anticancer therapy is based on traditional chemotherapy and radiotherapy. Both of these highly non-specific types of treatment have a number of serious side effects including wound healing complications. Radiotherapy and chemotherapy mostly affect rapidly dividing skin cells (e.g. keratinocytes), as well as fibroblasts, melanocytes, endothelial and immune cells. Currently, there are many strategies to improve wound healing in oncological patients, including various types of dressings, biomaterials, growth factors, and cell therapies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627262PMC
http://dx.doi.org/10.5114/ada.2018.72585DOI Listing

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