Using the case of Ulaanbaatar, Erdenet, and Darkhan cities from Mongolia, the study aimed to assess the contamination level and health risk assessment of heavy metals (As, Cr, Pb, Ni, and Zn) in urban soil. A total of 78 samples was collected from a variety of functional areas. The geoaccumulation index (I) and integrated pollution index (IPI) were used in pollution assessment, while the health risk was scored using a hazard quotient () and health index (HI) for non-carcinogenic heavy metals, as well as a lifetime average daily dose () for carcinogenic heavy metals. The results show that the concentration of heavy metals in the soil samples taken from Darkhan city, which presented "uncontaminated" values in terms of I for all metals, was relatively lower than other cities within the contamination assessment. Furthermore, the I value signified "uncontimated to heavily contaminated" soil in the Ulaanbaatar and Erdenet cities. Typically, as for the IPI that observed similar trends with I, the mean IPI values in Ulaanbaatar, Erdenet, and Darkhan were 1.33 (moderate level of pollution), 1.83 (moderate level of pollution), and 0.94 (low level of pollution), respectively. In terms of the assessment of potential health risk, there was a particular or different level of ingestion, dermal contact, and inhalation exposure pathway for human health. Among these three different pathways, the ingestion was estimated by the main contributor for health risk. Each value of HQ and HI indicated that soil heavy metals of studied cities were at a safe level (<1) or had the absence of a significant health risk there. In addition, the potential health risk for children was greater than for adults, where heavy metal values of HI for children had a high value compared to adults. We estimated carcinogenic risks through the inhalation exposure, and as a result, there were no significant risks for human health in the studied cities from three elements (As, Cr, and Ni).
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http://dx.doi.org/10.3390/ijerph16142552 | DOI Listing |
Front Immunol
January 2025
Department of Pathology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, China.
Colorectal cancer (CRC) is one of the most prevalent and deadly malignancies worldwide. Recently, ferroptosis, a novel form of regulated cell death characterized by iron dependency and lipid peroxidation, has garnered significant attention from researchers. The mechanisms underlying ferroptosis, including intracellular iron levels, lipid peroxidation, and antioxidant system regulation, offer new insights into cancer treatment strategies.
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January 2025
The First Affiliated Hospital of Army Military Medical University, Department of General Surgery, Chongqing, China.
Gastric cancer continues to be a leading global health concern, with current therapeutic approaches requiring significant improvement. While the disruption of iron metabolism in the advancement of gastric cancer has been well-documented, the underlying regulatory mechanisms remain largely unexplored. Additionally, the complement C5a-C5aR pathway has been identified as a crucial factor in gastric cancer development.
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February 2025
School of Agricultural Engineering and Food Science, Shandong University of Technology, Zibo 255049, Shandong, PR China. Electronic address:
Fe-loaded red radish anthocyanin (RRA) and zein composite nanoparticles (FZNPs) were firstly prepared to enhance the color and stability of RRA. The addition of Fe caused anthocyanin to form color chelates, enhancing its pH color sensitivity. The prepared FZNPs showed good stability and anthocyanin retention during long-term storage.
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February 2025
School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China. Electronic address:
Ferrous ions (Fe), the primary form of iron in cells, play a crucial role in various biological processes. The presence and absorption of Fe in food has an important impact on human health. Proper dietary intake and iron supplementation are conducive to prevent and treat iron-related diseases.
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February 2025
Nutrition and Seafood Laboratory (NuSea.Lab), School of Life and Environmental Sciences, Deakin University, Queenscliff, VIC, Australia. Electronic address:
Sustainable seaweed value chains necessitate accurate biomass biochemical characterisation that leads to product development, geographical authentications and quality and sustainability assurances. Underutilised yet abundantly available seaweed species require a thorough investigation of biochemical characteristics prior to their valorisation. Abundantly available Australian seaweed species lack such comprehensive investigations within the global seaweed industrial value chains.
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