The Raman probe plays an essential role in sensitive surface-enhanced Raman scattering (SERS) assay. Here, a novel Raman probe was developed by assembling gold nanoparticles in triangular pyramid DNA (TP-Au NPs). Such probe with intense electromagnetic hot spots can provide dramatically enhanced Raman scattering. Through assembling recognition DNA on one corner of the TP-DNA, the recognition event is definite and designable. The probe was characterized through TEM, and its SERS superiority was investigated. As models, circulating tumor cells and exosomes were detected with high sensitivity and selectivity by using this probe. Meanwhile, the developed SERS probe can also perform well in real world samples.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acsami.9b09465 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Surface Grafting of Graphene Flakes with Fluorescent Dyes: A Tailored Functionalization Approach.
Nanomaterials (Basel)
February 2025
NEST, Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, Italy.
The controlled functionalization of graphene is critical for tuning and enhancing its properties, thereby expanding its potential applications. Covalent functionalization offers a deeper tuning of the geometric and electronic structure of graphene compared to non-covalent methods; however, the existing techniques involve side reactions and spatially uncontrolled functionalization, pushing research toward more selective and controlled methods. A promising approach is 1,3-dipolar cycloaddition, successfully utilized with carbon nanotubes.
View Article and Find Full Text PDFStereodynamics of cold HD and D2 collisions with He.
J Chem Phys
March 2025
Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Nevada 89154, USA.
We present a comprehensive quantum mechanical study of stereodynamic control of HD + He and D2 + He collisions that have been probed experimentally by Perreault et al. [J. Phys.
View Article and Find Full Text PDFOptical Spectroscopic Probing and Atomic Visualization of the Motion of N-Heterocyclic Carbenes on Ag(111).
ACS Nano
March 2025
Department of Chemistry, University of Illinois Chicago, Chicago, Illinois 60607, United States.
The application of N-heterocyclic carbenes (NHCs) as versatile anchors for planar surface modifications has been well documented over the past decade. Despite its fundamental importance to the formation of self-assembled NHC monolayers on surfaces, the microscopic mechanism behind the mobility of NHCs has primarily been explored through theoretical studies; an atomic-level experimental understanding of NHC motion on surfaces remains elusive. Here, we combine tip-enhanced Raman spectroscopy (TERS) and scanning tunneling microscopy (STM) to investigate the mobility of a model NHC on Ag(111).
View Article and Find Full Text PDFRhodamine Based Chemosensors for Metal ions Detection: An Overview.
J Fluoresc
March 2025
Department of Chemistry, Guru Ghasidas Viswavidyalaya, Bilaspur, Chhattisgarh, 495009, India.
Today, water quality monitoring is crucial due to the health and environmental consequences of water pollution. Recently, various attempts have been made to construct rapid, sensitive, and selective heavy metal ion sensors. Fluorescent sensors are popular owing to their high specificity, sensitivity, and reversibility.
View Article and Find Full Text PDFFeO@Au magnetic SERS nanotags-based vertical flow immunoassay for simultaneous detection of fumonisin B1, aflatoxin B1 and deoxnivalenol.
Anal Chim Acta
April 2025
State Key Laboratory of Animal Nutrition and Feeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100193, China. Electronic address:
Agricultural products are usually contaminated by various mycotoxins, the rapid and sensitive detection of mycotoxins at the early stage is significant for food safety and human health. Here, we develop a rapid and ultrasensitive surface-enhanced Raman scattering-based vertical flow assay (VFA) for simultaneous detection of multiple mycotoxins by using FeO@Au magnetic SERS nanotags. In this competitive immunoassay, three test zones are designed on the sensing membrane, and modified with multiple capture antigens.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!