With the aid of three basic organic compounds, 2-pyrazinoylguanidine, 3-amino-2-pyrazinoylguanidine, and 3,5-diamino-6-fluoro-2-pyrazinoylguanidine, urea was shown to be secreted by the renal tubules of the dog both from the lumen and into the lumen independent of urine flow.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC280354 | PMC |
| http://dx.doi.org/10.1073/pnas.85.11.4030 | DOI Listing |
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