AI Article Synopsis
- Metabolic Syndrome (MetS) consists of various health factors that heighten the risk of heart disease and type 2 diabetes (T2DM), but its link to lung function hasn't been thoroughly studied.
- A study in northern India analyzed 100 patients with MetS, aged 25-65, using pulmonary function tests (spirometry) to assess lung abnormalities.
- Results showed that patients with MetS had significantly lower lung capacities and functions, with both the number of MetS components and the severity of lung function decline increasing, particularly among certain age groups.
Article Abstract
Introduction: Metabolic Syndrome (MetS) is defined as a constellation of an interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of atherosclerotic cardiovascular disease and T2DM. Although the link between impaired lung function and cardiovascular events and T2DM has been recognized, the association between impaired lung function and MetS has not been comprehensively assessed.
Material And Methods: A cross sectional prevalence study was done in tertiary care hospital in northern India on 100 patients of the age between 25-65 years who fulfilled the IDF criteria for MetS to evaluate pulmonary function test (Spirometry) abnormalities.
Results: Maximum number of patients were in 31-40 years of age group (45%) followed by those aged 41-50 year (26%), < 30 years (15%), >50 years (14%). Mean age of patients was 39.59±8.67 year. In this cross-sectional study, patients with Metabolic Syndrome showed significantly lower FVC % predicted (P< 0.001), FEV1 % predicted (P< 0.001) as compared to the group without Metabolic Syndrome. There was a strong linear decrease in FVC and FEV1 % predicted as the number of components of MetS increases. We observed that 28% of the male and 46.6% of female patients showed restrictive ventilatory pattern and 7% of male and 13.4% of female patients showed mixed pattern.
Conclusion: All MetS components were associated with pulmonary function impairment. As the number of MetS components increases, patients had more severe decline in pulmonary functions.
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