AI Article Synopsis
- The study aimed to evaluate heart rate variability (HRV) in patients with pulmonary hypertension (PH) and examine if sleep apnea worsens HRV effects.
- Researchers compared 41 PH patients to 41 healthy controls, discovering that PH patients had significantly lower HRV across different measures, including high frequency and low frequency metrics.
- The findings showed that sleep apnea did not further impact HRV in PH patients, suggesting that the impaired HRV seen in these individuals was not exacerbated by the presence of sleep apnea.
Article Abstract
Objectives: Our aims were to evaluate HRV in pulmonary hypertension (WHO Group 1 and 4) compared to control subjects, and to assess whether the presence of sleep apnea in those with pulmonary hypertension would be deleterious and cause greater impairment in HRV.
Methods: This retrospective case-control study analyzed electrocardiogram segments obtained from diagnostic polysomnography.
Results: Forty-one pulmonary hypertension patients were compared to 41 age, sex and apnea-hypopnea index matched healthy controls. The pulmonary hypertension group had decreased high frequency, very low frequency, low frequency, and percentage of normal R-R intervals that differ by > 50 ms compared to control subjects. Moderate to severe right ventricle dysfunction on echocardiography was a predictor of lower high frequency in pulmonary hypertension patients.
Conclusions: There were no differences in any HRV measures in pulmonary hypertension patients with or without sleep apnea. Impaired HRV was demonstrated in pulmonary hypertension patients however, the presence of sleep apnea did not appear to further reduce vagal modulation.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611942 | PMC |
| http://dx.doi.org/10.1016/j.heliyon.2019.e02034 | DOI Listing |
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