In this issue of Immunity, Deniset et al. (2019) reveal a reparative function for GATA6 pericardial cavity macrophages following cardiac injury. Their findings call for reconsideration of surgical procedures that involve the removal of the pericardium.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.immuni.2019.06.020 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Impacts of extract on biomarker levels, macrophage count, and lesion area in an endometriotic rat model.
Narra J
December 2024
Doctoral Program of Medical Science, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia.
Endometriosis is a gynecological disorder characterized by chronic inflammation, anatomical changes, prolonged pain, and infertility. On the other hand, is recognized for its pharmacological effects, which might be beneficial in managing endometriosis. The aim of the study was to investigate the pharmacological effects of as a potential therapy for endometriosis by using an animal model.
View Article and Find Full Text PDFInjection of ROS-Responsive Hydrogel Loaded with IL-1β-targeted nanobody for ameliorating myocardial infarction.
Bioact Mater
April 2025
School of Medicine South China University of Technology, Guangzhou, Guangdong, 510006, China.
The cardiac microenvironment profoundly restricts the efficacy of myocardial regeneration tactics for the treatment of myocardial infarction (MI). A prospective approach for MI therapeutics encompasses the combined strategy of scavenging reactive oxygen species (ROS) to alleviate oxidative stress injury and facilitating macrophage polarization towards the regenerative M2 phenotype. In this investigation, we fabricated a ROS-sensitive hydrogel engineered to deliver our previously engineered IL-1β-VHH for myocardial restoration.
View Article and Find Full Text PDFUterine-derived exosomes induce the M2 polarization of macrophages via miR-210-3p/ATP5D to promote endometriosis progression.
Life Sci
January 2025
Department of Obstetrics and Gynecology, The Second Xiangya Hospital of Central South University, Changsha 410011, China. Electronic address:
Aims: Endometriosis development is associated with peritoneal immune microenvironment abnormality; however, the specific mechanism is uncertain. We aimed to investigate the effects and underlying mechanisms of uterine cavity-derived exosomes on macrophage polarization and endometriosis progression.
Materials And Methods: Uterine cavity-derived exosomes, miR-210-3p inhibitor or siATP5D were used to treat macrophages.
Formulation of different concentrations of nanosilver fluoride incorporated dentifrices, evaluation of its cytotoxicity and antimicrobial effect on Streptococcus mutans.
J Indian Soc Pedod Prev Dent
October 2024
Department of Pediatric and Preventive Dentistry, Santosh Deemed to be University, Santosh Dental College and Hospital, Ghaziabad, Uttar Pradesh, India.
Article Synopsis
- The study investigates the effectiveness and safety of dentifrices containing Nano silver fluoride (NSF) against the bacteria Streptococcus mutans, which causes tooth decay.
- Researchers synthesized NSF particles and created dentifrices with varying concentrations of NSF, assessing their antimicrobial properties using an agar diffusion method and cytotoxicity on mouse macrophage cells.
- Results showed that NSF dentifrices inhibited bacterial growth effectively while also evaluating their impact on cell viability to ensure safety for use in oral health products.
The Immunophenotype and the Odontogenic Commitment of Dental Pulp Stem Cells Co-Cultured with Macrophages Under Inflammatory Conditions Is Modulated by Complex Magnetic Fields.
Int J Mol Sci
December 2024
Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy.
Dental inflammatory diseases remain a challenging clinical issue, whose causes and development are still not fully understood. During dental caries, bacteria penetrate the tooth pulp, causing pulpitis. To prevent pulp necrosis, it is crucial to promote tissue repair by recruiting immune cells, such as macrophages, able to secrete signal molecules for the pulp microenvironment and thus to recruit dental pulp stem cells (DPSCs) in the damaged site.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!