Coumarins are a very large family of compounds containing the unique 2-chromen-2-one motif, as it is known according to IUPAC nomenclature. Coumarin derivatives are widely found in nature, especially in plants and are constituents of several essential oils. Up to now, thousands of coumarin derivatives have been isolated from nature or produced by chemists. More recently, the coumarin platform has been widely adopted in the design of small-molecule fluorescent chemosensors because of its excellent biocompatibility, strong and stable fluorescence emission, and good structural flexibility. This scaffold has found wide applications in the development of fluorescent chemosensors in the fields of molecular recognition, molecular imaging, bioorganic chemistry, analytical chemistry, materials chemistry, as well as in the biology and medical science communities. This review focuses on the important progress of coumarin-based small-molecule fluorescent chemosensors during the period of 2012-2018. This comprehensive and critical review may facilitate the development of more powerful fluorescent chemosensors for broad and exciting applications in the future.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.chemrev.9b00145 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Novel Nitrogen Hybrid F Sensors Based on ESIPT Mechanism Achieving Super Low Detection Limits.
Luminescence
January 2025
Department of Psychiatry, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
Two novel nitrogen hybrid fluorescent sensors based on the ESIPT mechanism were successfully synthesized for the detection of fluoride ions (F), and they exhibit high sensitivity and selectivity with a fast response. The detection limits even reach the parts per billion level. With the addition of F, both sensors showed a ratiometric fluorescence change with a large Stokes shift.
View Article and Find Full Text PDFStimuli-Chromic Oxazolidine Latex Nanoparticles for Dual-Responsive pH-Sensors and Rewritable Halochromic Papers: A Physicochemical Study on Colorimetric and Fluorimetric Signals.
ACS Appl Mater Interfaces
January 2025
Department of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan 45137-66731, Iran.
Oxazolidine is a new category of stimuli-chromic compounds that has unique intelligent behaviors such as halochromism, hydrochromism, solvatochromism, and ionochromism, all of which have potential applications for designing and constructing chemosensors by using functionalized-polymer nanocarriers. Here, the poly(MMA--HEMA) based nanoparticles were synthesized by emulsion copolymerizing methyl methacrylate (MMA) and 2-hydroxyethyl methacrylate (HEMA) in different copolymer compositions. The poly(MMA--HEMA) based nanoparticles were modified physically with tertiary amine-functionalized oxazolidine (as an intelligent pH-responsive organic dye) to prepare halochromic latex nanoparticles.
View Article and Find Full Text PDFRhodamine based turn-on dual mode chemosensor for the selective recognition of nickel ions: practical and theoretical applications.
RSC Adv
January 2025
Bioorganic Laboratory, Department of Chemistry, University of Delhi Delhi-110007 India
This work presents the development of a rhodamine-based colorimetric and turn-on fluorescent chemosensor (P1) designed for selective recognition of Ni ions. Chemosensor P1 exhibited remarkable sensitivity and selectivity for Ni ions, exhibiting clear colorimetric and fluorescence responses. The binding interactions were meticulously examined using UV-Vis.
View Article and Find Full Text PDFAbsorption, Steady-State Fluorescence and Solvent Effect Studies of Fluorescent Haloarchaeal Bacterioruberin.
J Fluoresc
January 2025
Central Research Laboratory, Kastamonu University, 37200, Kastamonu, Turkey.
Fluorescence characterization of halophilic archaeal C50 carotenoid-bacterioruberin extracts was investigated using UV/Vis and steady-state fluorescence spectrophotometry in solvents with different polarity. Different extracts showed maximum absorption and fluorescence wavelengths between 369-536 nm and 540-569 nm. Stokes' shifts varied between 50-79 nm depending on the solvent.
View Article and Find Full Text PDFDesign and synthesis of a carbohydrate-derived chemosensor for selective Ni(II) ion detection: A turn-off approach.
Carbohydr Res
March 2025
Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi, 110007, India; Department of Chemistry, Ramjas College, University of Delhi, Delhi, 110007, India. Electronic address:
Nickel, an essential transition metal, plays a vital role in biological systems and industries. However, exposure to nickel can cause severe health issues, such as asthma, dermatitis, pneumonitis, neurological disorders, and cancers of the nasal cavity and lungs. Due to nickel's toxicity and extensive industrial use, efficient sensors for detecting Ni ions in environmental and biological contexts are essential.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!