Salinaphthoquinones A-E (-) were isolated from a marine strain, recovered from sediments of the St. Peter and St. Paul Archipelago, Brazil. The structures of the compounds were elucidated using a combination of spectroscopic (NMR, IR, HRESIMS) data, including single-crystal X-ray diffraction analysis. A plausible biosynthetic pathway for - is proposed. Compounds to displayed moderate activity against and with MIC values of 125 to 16 μg/mL.
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