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Positive Lymph Node Status Before and After Neoadjuvant Chemoradiotherapy Improves Prediction of Disease-Free Survival in Esophageal Squamous Cell Carcinoma Patients.
Ann Surg Oncol
January 2025
Departments of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Background: This study proposes a modified lymph node (LN) staging category (BALN) on the basis of the number of positive LNs before (prepN) and after (ypN) neoadjuvant chemoradiotherapy (nCRT) to improve prognostic stratification in esophageal squamous cell carcinoma (ESCC).
Patients And Methods: A total of 381 patients with ESCC who underwent nCRT at three medical centers were retrospectively enrolled. The ypN categories were scored according to the eighth edition of the American Joint Committee of Cancer (AJCC) staging manual.
Improving care in elderly neurosurgery initiative guideline on management of chronic subdural haematoma in older people-relevance for the geriatrician.
Age Ageing
January 2025
North Bristol NHS Trust - Geriatric Medicine, Southmead Hospital, Southmead Road, Bristol BS10 5NB, UK.
Chronic subdural haematoma (cSDH) is a common subtype of traumatic brain injury, typically affecting older people living with frailty and multimorbidity. Until now, no published guideline has existed internationally to guide management, perhaps explaining why the care of the older cSDH patient varies between neurosurgical centres. The Improving Care in Elderly Neurosurgery Initiative guideline is the first guideline dedicated to the care of patients with cSDH across the entire patient pathway, from initial presentation through to rehabilitation and discharge after surgery.
View Article and Find Full Text PDFEvaluation of hepatic steatosis in obese children and adolescents using immune-inflammatory markers and shear wave elastography.
J Ultrason
January 2025
Radiology, Malatya Training and Research Hospital, Malatya, Turkey.
Aim: To investigate the changes in liver stiffness and immune-inflammatory markers associated with obesity and the degree of hepatic steatosis in obese children and adolescents.
Methods: A total of 76 obese children and adolescents aged 6-18 years, with body mass index percentiles >95th, were included in the study. Patients with metabolic syndrome, diabetes mellitus, and chronic liver disease were excluded.
Percutaneous Pinning for Proximal Humerus Fractures: Insights From a Five-Year Retrospective Study.
Cureus
December 2024
Orthopaedics and Traumatology, University Hospital Galway, Galway, IRL.
Introduction: Proximal humerus fractures are a common orthopedic challenge, particularly in older adults. Percutaneous pinning, a minimally invasive technique, aims to stabilize fractures while preserving soft tissue integrity. This study evaluates the functional and radiological outcomes of patients treated with percutaneous pinning at a single center over five years.
View Article and Find Full Text PDFA Case of a Short Stature Patient With Marfan Syndrome: A Tale of Wide Mediastinum.
Cureus
December 2024
Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, USA.
Marfan syndrome (MFS), an inherited connective tissue disorder, is caused by a mutation in the FBN1 gene. MFS is characterized by complex manifestations involving musculoskeletal, cardiovascular, and ocular systems. The usual presentation for suspecting diagnosis in an individual with aortic root disease is tall stature in addition to other features that fulfill Ghent criteria.
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