AI Article Synopsis
- The study aimed to compare MRI findings in patients with primary and secondary pseudotumor cerebri (PTC) to assess their diagnostic value and link them with symptoms and lab results.
- Twenty-eight PTC patients were evaluated alongside a control group of 20 people, using the Modified Dandy Criteria for diagnosis and extensive MRI assessments.
- Key MRI markers identified included posterior flattening of the globe and optic nerve sheath distention, which showed high specificity, making them significant indicators for diagnosing PTC.
Article Abstract
The objective of our study was to provide a comparative assessment of previously reported magnetic resonance imaging (MRI) parameters in primary and secondary pseudotumor cerebri (PTC) patients, to examine their diagnostic contribution, and to evaluate their association with symptoms, neuro-ophthalmological findings, laboratory results, and cerebrospinal fluid characteristics. Twenty-eight consecutive patients with PTC were included in the study. Age- and sex-matched 20 individuals with normal neurologic examination served as the control group. Modified Dandy Criteria were used for the diagnosis of PTC. Orbital and cranial MRI and MR venography of all patients and controls were assessed by three radiologists. According to our study, posterior flattening of the globe (64% sensitive, 100% specific), optic nerve sheath distention (46% sensitive, 100% specific), vertical tortuosity of the optic nerve (30% sensitive, 95% specific), and partial empty sella (43% sensitive, 100% specific) emerged as particularly valuable markers for a diagnosis of PTC.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619944 | PMC |
| http://dx.doi.org/10.1080/01658107.2018.1493514 | DOI Listing |
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