Objectives: To develop and formulate a new experimental dentifrice with and without fluoride based on the peel and the fruit of the (tumbo) and also to evaluate its antimicrobial activity against seven bacterial strains.

Methods: The sample was calculated using the mean comparison formula, obtaining wells ( = 12) for each of the strains evaluated: , , , , , , and . The antibacterial activity of the dentifrice was evaluated by the direct contact technique.

Results: It was found that the highest antimicrobial activity was only present in pulp-based dentifrices against strains of 21.0 ± 1.8, 16.3 ± 3.9, 22.1 ± 1.3, and 21.0 ± 1.3. However, in comparison with other strains such as , , and , the peel-based dendrifrice of obtained the highest antimicrobial activity.

Conclusion: The experimental dentifrice based on had an antibacterial effect against the seven microbial strains during the first 24 and 48 hours.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595319PMC
http://dx.doi.org/10.1155/2019/9056590DOI Listing

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