AI Article Synopsis
- Acellular dermal allograft (AlloDerm) and cartilage perichondrium are both used to repair tympanic membrane perforations, but there's limited research comparing their effectiveness.
- In a study of 61 patients split into two groups, AlloDerm showed a closure success rate of 88.9%, while perichondrium showed 82.4%.
- Both materials yielded similar improvements in hearing, but AlloDerm had a shorter surgical time and avoids additional incisions for graft harvesting, making it a preferable alternative.
Article Abstract
Acellular dermal allograft (AlloDerm) and cartilage perichondrium are two common materials used for repair of tympanic membrane perforations (TMPs). To date, comparative evaluations of their efficacy have rarely been reported. To compare anatomical and audiological outcomes between AlloDerm and cartilage perichondrium in type I tympanoplasty. A total of 61 patients of TMP were studied. In total, 27 patients (Group 1) underwent AlloDerm myringoplasty, and the remaining 34 patients (Group 2) underwent perichondrium myringoplasty. Operating time, closure rate and hearing gain were compared between Groups 1 and 2. Successful closure rates at 6-month follow-up were 88.9% (Group 1) and 82.4% (group 2). The average improvement of air-bone gap (ABG) was 13.5 ± 11.8 dB for Group 1 and 13.1 ± 13.1 dB for Group 2. The difference in between preoperative and 6 months postoperative ABG values was statistically significant ( < .001). Success rates and improvement of hearing level were similar for the AlloDerm (Group 1) and the cartilage perichondrium (Group 2) groups. However, AlloDerm requires shorter operative time and avoids the incisions in the harvest of allografts. Our results suggest that AlloDerm can be recommended as an attractive alternative to cartilage grafts.
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| http://dx.doi.org/10.1080/00016489.2019.1637541 | DOI Listing |
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