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Investigation of the Effects of Biochemical Parameters on Alzheimer's Disease. | LitMetric

Investigation of the Effects of Biochemical Parameters on Alzheimer's Disease.

Am J Alzheimers Dis Other Demen

Department of Neurology, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey.

Published: July 2020

AI Article Synopsis

Article Abstract

Background: The most common type of dementia is an Alzheimer's disease which is a major concern in growing chronic diseases in the geriatric society, and its connection with biochemistry has not been sufficiently understood.

Objective: This study aims to evaluate the effects of blood biochemistry on Alzheimer's disease.

Method: Eight participants aged 55+ with Alzheimer's disease were analyzed. A cross-sectional work has conducted. Eighty patients have been divided into 2 groups as group A and group B according to laboratory findings including glycosylated hemoglobin, high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol (TC), triglycerides (TGA), vitamin D, folic acid, and vitamin B. Mean Mini-Mental State Examination scores between these different 2 groups have been compared.

Results: High levels of HDL, vitamin D, and folic acid correlate with cognitive scores, whereas high levels of total cholesterol, HbA1c, LDL show a negative effect on cognition scores.

Conclusion: High-density lipoprotein, vitamin D, folic acid, cholesterol, HgA1c, and LDL have an effect on dementia.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653365PMC
http://dx.doi.org/10.1177/1533317519862108DOI Listing

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