DNase I-Responsive Calixpyridinium-Mediated DNA Aggregation.

Langmuir

Tianjin Key Laboratory of Structure and Performance for Functional Molecules, MOE Key Laboratory of Inorganic-Organic Hybrid Functional Material Chemistry, College of Chemistry , Tianjin Normal University, Binshuixi Road 393 , Xiqing District, Tianjin 300387 , China.

Published: August 2019

In this work, cationic macrocyclic calixpyridinium was employed as a new strategy to condense DNA. Moreover, the degradation of DNA by DNase I could lead to the calixpyridinium-DNA supramolecular aggregates being dissipated. Therefore, the present system is potentially applicable as the targeted drug delivery model at DNase I-overexpressed sites.

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.langmuir.9b01116DOI Listing

Publication Analysis

Top Keywords

dnase i-responsive
4
i-responsive calixpyridinium-mediated
4
calixpyridinium-mediated dna
4
dna aggregation
4
aggregation work
4
work cationic
4
cationic macrocyclic
4
macrocyclic calixpyridinium
4
calixpyridinium employed
4
employed strategy
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!