Background: Hepatitis E Virus (HEV) infection is a major concern regarding morbidity and mortality among pregnant women especially in developing countries. The objective of this study was to determine the characteristics and obstetric outcomes in pregnant women with Acute Hepatitis E Virus Infection in tertiary care hospital of Himachal Pradesh.
Methods: Prospective observational study has been done in the department of Obstetrics and Gynaecology and department of Medicine and Emergency Medicine among all the pregnant women who were sero-positive for hepatitis E viral marker in two consecutive years. Information regarding basic characteristics of pregnant women and obstetric outcome has been collected.
Results: Among 30 pregnant women with hepatitis E viral infection, a case fatality ratio of 8.0% for hepatitis E infection was found. 13.3% of the pregnancies ended up as intra uterine death. Most common age group affected was below 25 years. Mode of delivery among 70% of the women was normal vaginal delivery though 30% women delivered prematurely.
Conclusions: This prospective case series of 30 pregnant women with acute hepatitis E viral infection, indicate poor maternal, obstetric and foetal outcome among pregnant women with hepatitis E viral infection.
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J Cardiothorac Surg
January 2025
Semmelweis University Heart and Vascular Centre, Budapest, 1122, Hungary.
Background: Aortic dissection occurs rarely during pregnancy but carries a significantly high vital risk for both the mother and the fetus. Early diagnosis and treatment are critical for a successful outcome.
Case Presentation: A 32-year-old pregnant woman at 31 weeks of gestation began experiencing shortness of breath, chest pain, and palpitations, which were attributed to an anxiety disorder she had been previously diagnosed with.
BMC Infect Dis
January 2025
Department of Family Medicine, Epidemiology & Community Health, School of Health Sciences, Kenyatta University, Nairobi, Kenya.
Background: HIV and HBV remain significant public health challenges characterized by high prevalence, morbidity, and mortality, especially among women of reproductive age in Uganda. Patients with HBV do not receive routine counselling and education, and there are limited resources for laboratory investigation coupled with a high loss to follow-up. This study set out to assess barriers and facilitators of integrated viral hepatitis B C and HIV care model to optimize screening uptake among mothers and newborns at health facilities in Koboko District, west Nile sub-region, Uganda.
View Article and Find Full Text PDFArch Gynecol Obstet
January 2025
MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK.
Purpose: Observational studies have suggested negative associations between maternal 25-hydroxyvitamin D (25(OH)D) status and risk of hypertensive disorders of pregnancy [pregnancy-induced hypertension (PIH) and preeclampsia (PET)]. Data from intervention studies are limited. We hypothesised that vitamin D supplementation would lower maternal blood pressure (BP) during pregnancy and reduce the incidence of hypertensive disorders of pregnancy.
View Article and Find Full Text PDFExpert Opin Pharmacother
January 2025
Mediprobe Research Inc, London, ON, Canada.
Introduction: Alopecia affects many individuals, with androgenetic alopecia (AGA) being the most common form in both men and women. The exact etiology of AGA is unclear. The systemic treatments of AGA include 5-alpha reductase inhibitors (finasteride, dutasteride), low-dose oral minoxidil.
View Article and Find Full Text PDFJ Matern Fetal Neonatal Med
December 2025
Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Objective: There is an increase in the application data of Extracorporeal Membrane Oxygenation (ECMO) in perinatal women, particularly since the outbreak of coronavirus disease 2019. Therefore, we reviewed publications on the use of ECMO in pregnant and postpartum women and analyzed the maternal and fetal outcomes, updated the progress of ECMO in perinatal women.
Methods: We conducted a systematic literature search across PubMed, EMBASE, Cochrane Library, and the International Clinical Trials Registry (ICTRP), yielding 30 eligible clinical studies that investigated the application of ECMO during pregnancy.
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