AI Article Synopsis
- α4β1 integrin and VEGFR2 work together as a receptor complex that interacts with VEGF in chronic lymphocytic leukemia (CLL) cells.
- This interaction suggests that α4β1 integrin has a new and significant role in the development of CLL.
- The findings highlight how understanding these receptors could lead to better insights into CLL pathology and potential treatments.
Article Abstract
α4β1 integrin and VEGFR2 function as a receptor complex for VEGF in CLL cells. Contribution to VEGF functions in CLL is a novel pathological role for α4β1 integrin in this malignancy.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650728 | PMC |
| http://dx.doi.org/10.1182/bloodadvances.2019000019 | DOI Listing |
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