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Ultra high dose rate Synchrotron Microbeam Radiation Therapy. Preclinical evidence in view of a clinical transfer. | LitMetric

Ultra high dose rate Synchrotron Microbeam Radiation Therapy. Preclinical evidence in view of a clinical transfer.

Radiother Oncol

Inserm UA7, Synchrotron Radiation for Biomedical Research (STROBE), Université Grenoble Alpes - ID17, Installation Européenne du Rayonnement Synchrotron (ESRF) CS 40220, Grenoble Cedex 9, France. Electronic address:

Published: October 2019

AI Article Synopsis

Article Abstract

This paper reviews the current state of the art of an emerging form of radiosurgery dedicated to brain tumour treatment and which operates at very high dose rate (kGy·s). Microbeam Radiation Therapy uses synchrotron-generated X-rays which triggered normal tissue sparing partially mediated by FLASH effect.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radonc.2019.06.030DOI Listing

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